Browsing by Author "Burak Tüzün"
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Molecular hybrids integrated with imidazole and hydrazone structural motifs: Design, synthesis, biological evaluation, and molecular docking studies
Michael Tapera; Hüseyin Kekeçmuhammed; Emin Sarıpınar; Murat Doğan; Burak Tüzün; Ümit M Koçyiğit; Feyza Nur Çetin (Elsevier, 2023/12/1)In the present work, a series of compounds containing imidazole and hydrazone structural frameworks were synthesized and characterized using various spectral techniques, including 1H NMR, 13C NMR, FTIR, and HRMS. Synthesized ... -
Piperazin incorporated Schiff Base derivatives: Assessment of in vitro biological activities, metabolic enzyme inhibition properties, and molecular docking calculations
Arif Mermer; Burak Tüzün; Sevgi Durna Daştan; Ümit M Koçyiğit; Feyza Nur Çetin; Özge Çevik (WİLEY, 2023/11)The cytotoxic activities of the compounds were determined by the 3‐(4, 5‐dimethylthiazolyl‐2)‐2,5‐diphenyltetrazolium bromide (MTT) method in human breast cancer (MCF‐7), human cervical cancer (HeLa), and mouse fibroblast ...